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The chance for significant respiration difficulties is greater when you start this medication and after a dose enhance, or if you take the incorrect dose/power. Getting this medication with Liquor or other prescription drugs that could cause drowsiness or respiration difficulties may lead to quite really serious facet effects, such as Demise. Also, other remedies can have an effect on the removal of codeine from the body, which may affect how codeine is effective.

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clomipramine decreases effects of codeine by influencing hepatic enzyme CYP2D6 metabolism. Use Warning/Keep track of. Prevents conversion of codeine to its active metabolite morphine.

clozapine decreases effects of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Warning/Monitor. Helps prevent conversion of codeine to its Energetic metabolite morphine.

Employing this medicine with any of the following may well result in an increased possibility of specific facet effects but may very well be unavoidable in some instances. If used with each other, your medical professional may perhaps alter the dose or how often you use this drugs, or Supply you with Unique instructions about the use of food items, Alcoholic beverages, or tobacco.

diazepam buccal and codeine the two maximize sedation. Prevent or Use Alternate Drug. Limit use to people for whom option cure selections are inadequate

Retain a list of each of the merchandise you employ (together with prescription/nonprescription medications and herbal products) and share it with your health care provider and pharmacist. Do not get started, halt, or change the dosage of any medicines without your health practitioner's approval.

Retail store at room temperature far from gentle and dampness. Unique brands of this medication have various storage desires. Check out the merchandise bundle for Guidelines regarding how to retail store your brand, or talk to your pharmacist. Retain all prescription drugs from children and Animals.

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